Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.

The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is increasing evidence that common genetic variants may play a role. We investigated the contribution of polymorphisms in two genes implicated in the pathogenesis of colorectal cancer, cyclin D1 (CCND1) and...

Полное описание

Библиографические подробности
Главные авторы: Porter, T, Richards, F, Houlston, R, Evans, D, Jankowski, J, Macdonald, F, Norbury, G, Payne, S, Fisher, SA, Tomlinson, I, Maher, E
Формат: Journal article
Язык:English
Опубликовано: 2002