Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.

The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is increasing evidence that common genetic variants may play a role. We investigated the contribution of polymorphisms in two genes implicated in the pathogenesis of colorectal cancer, cyclin D1 (CCND1) and...

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Main Authors: Porter, T, Richards, F, Houlston, R, Evans, D, Jankowski, J, Macdonald, F, Norbury, G, Payne, S, Fisher, SA, Tomlinson, I, Maher, E
格式: Journal article
语言:English
出版: 2002