The EuroPhysiome, STEP and a roadmap for the virtual physiological human.

Biomedical science and its allied disciplines are entering a new era in which computational methods and technologies are poised to play a prevalent role in supporting collaborative investigation of the human body. Within Europe, this has its focus in the virtual physiological human (VPH), which is a...

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Main Authors: Fenner, J, Brook, B, Clapworthy, G, Coveney, P, Feipel, V, Gregersen, H, Hose, DR, Kohl, P, Lawford, P, McCormack, K, Pinney, D, Thomas, SR, Van Sint Jan, S, Waters, S, Viceconti, M
Format: Journal article
Language:English
Published: 2008
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author Fenner, J
Brook, B
Clapworthy, G
Coveney, P
Feipel, V
Gregersen, H
Hose, DR
Kohl, P
Lawford, P
McCormack, K
Pinney, D
Thomas, SR
Van Sint Jan, S
Waters, S
Viceconti, M
author_facet Fenner, J
Brook, B
Clapworthy, G
Coveney, P
Feipel, V
Gregersen, H
Hose, DR
Kohl, P
Lawford, P
McCormack, K
Pinney, D
Thomas, SR
Van Sint Jan, S
Waters, S
Viceconti, M
author_sort Fenner, J
collection OXFORD
description Biomedical science and its allied disciplines are entering a new era in which computational methods and technologies are poised to play a prevalent role in supporting collaborative investigation of the human body. Within Europe, this has its focus in the virtual physiological human (VPH), which is an evolving entity that has emerged from the EuroPhysiome initiative and the strategy for the EuroPhysiome (STEP) consortium. The VPH is intended to be a solution to common infrastructure needs for physiome projects across the globe, providing a unifying architecture that facilitates integration and prediction, ultimately creating a framework capable of describing Homo sapiens in silico. The routine reliance of the biomedical industry, biomedical research and clinical practice on information technology (IT) highlights the importance of a tailor-made and robust IT infrastructure, but numerous challenges need to be addressed if the VPH is to become a mature technological reality. Appropriate investment will reap considerable rewards, since it is anticipated that the VPH will influence all sectors of society, with implications predominantly for improved healthcare, improved competitiveness in industry and greater understanding of (patho)physiological processes. This paper considers issues pertinent to the development of the VPH, highlighted by the work of the STEP consortium.
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spelling oxford-uuid:b4219bd0-b354-47eb-95a5-5c172a67a9462022-03-27T04:23:59ZThe EuroPhysiome, STEP and a roadmap for the virtual physiological human.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b4219bd0-b354-47eb-95a5-5c172a67a946EnglishSymplectic Elements at Oxford2008Fenner, JBrook, BClapworthy, GCoveney, PFeipel, VGregersen, HHose, DRKohl, PLawford, PMcCormack, KPinney, DThomas, SRVan Sint Jan, SWaters, SViceconti, MBiomedical science and its allied disciplines are entering a new era in which computational methods and technologies are poised to play a prevalent role in supporting collaborative investigation of the human body. Within Europe, this has its focus in the virtual physiological human (VPH), which is an evolving entity that has emerged from the EuroPhysiome initiative and the strategy for the EuroPhysiome (STEP) consortium. The VPH is intended to be a solution to common infrastructure needs for physiome projects across the globe, providing a unifying architecture that facilitates integration and prediction, ultimately creating a framework capable of describing Homo sapiens in silico. The routine reliance of the biomedical industry, biomedical research and clinical practice on information technology (IT) highlights the importance of a tailor-made and robust IT infrastructure, but numerous challenges need to be addressed if the VPH is to become a mature technological reality. Appropriate investment will reap considerable rewards, since it is anticipated that the VPH will influence all sectors of society, with implications predominantly for improved healthcare, improved competitiveness in industry and greater understanding of (patho)physiological processes. This paper considers issues pertinent to the development of the VPH, highlighted by the work of the STEP consortium.
spellingShingle Fenner, J
Brook, B
Clapworthy, G
Coveney, P
Feipel, V
Gregersen, H
Hose, DR
Kohl, P
Lawford, P
McCormack, K
Pinney, D
Thomas, SR
Van Sint Jan, S
Waters, S
Viceconti, M
The EuroPhysiome, STEP and a roadmap for the virtual physiological human.
title The EuroPhysiome, STEP and a roadmap for the virtual physiological human.
title_full The EuroPhysiome, STEP and a roadmap for the virtual physiological human.
title_fullStr The EuroPhysiome, STEP and a roadmap for the virtual physiological human.
title_full_unstemmed The EuroPhysiome, STEP and a roadmap for the virtual physiological human.
title_short The EuroPhysiome, STEP and a roadmap for the virtual physiological human.
title_sort europhysiome step and a roadmap for the virtual physiological human
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