Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, and to rat heart xenografts, using monoclonal antibodies to CD4 and CD8.

Mice given a single short course of anti-CD4 and anti-CD8 monoclonal antibodies (mAb) became tolerant of major histocompatibility complex (MHC)-incompatible vascularized heart allografts in a donor- and organ-specific manner. T cell depletion was not important, as blocking antibodies were equally ef...

Celý popis

Podrobná bibliografie
Hlavní autoři: Chen, Z, Cobbold, S, Metcalfe, S, Waldmann, H
Médium: Journal article
Jazyk:English
Vydáno: 1992