Systemic lupus erythematosus and nephritis: severe relapse with disappearance of antinuclear antibodies.

Exacerbations of systemic lupus erythematosus with active renal disease are almost always associated with high plasma titres of antinuclear factor (ANF) and DNA-binding antibody (anti-ds DNA). We describe a patient with classical systemic lupus erythematosus and initial high titres of antinuclear an...

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Detalhes bibliográficos
Main Authors: White, N, Winearls, C, Ledingham, J
Formato: Journal article
Idioma:English
Publicado em: 1980
Descrição
Resumo:Exacerbations of systemic lupus erythematosus with active renal disease are almost always associated with high plasma titres of antinuclear factor (ANF) and DNA-binding antibody (anti-ds DNA). We describe a patient with classical systemic lupus erythematosus and initial high titres of antinuclear antibodies in whom severe relapse resulting in renal failure coincided with a prolonged reversion to normal of these serological indices.