The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

Genetic variants that associate with DNA methylation at CpG sites (methylation quantitative trait loci, meQTLs) offer a potential biological mechanism of action for disease associated SNPs. We investigated whether meQTLs exist in abdominal subcutaneous adipose tissue (SAT) and if CpG methylation ass...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Drong, A, Nicholson, G, Hedman, A, Meduri, E, Grundberg, E, Small, K, Shin, S, Bell, J, Karpe, F, Soranzo, N, Spector, T, McCarthy, M, Deloukas, P, Rantalainen, M, Lindgren, C
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2013