Outcome of invasive pneumococcal disease: a UK based study
Methods - The records of 106 children aged less than 5 years with invasive disease caused by Streptococcus pneumoniae were reviewed. Results - The clinical manifestations were meningitis (37%), upper respiratory tract infection (24%), pneumonia (19%), and occult bacteraemia (18%). One child died and...
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Journal article |
| Hizkuntza: | English |
| Argitaratua: |
2000
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| _version_ | 1826292241839161344 |
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| author | Shackley, F Knox, K Morris, J Crook, D Griffiths, D Mayon-White, R George, R Willocks, L Moxon, E Gr, O |
| author_facet | Shackley, F Knox, K Morris, J Crook, D Griffiths, D Mayon-White, R George, R Willocks, L Moxon, E Gr, O |
| author_sort | Shackley, F |
| collection | OXFORD |
| description | Methods - The records of 106 children aged less than 5 years with invasive disease caused by Streptococcus pneumoniae were reviewed. Results - The clinical manifestations were meningitis (37%), upper respiratory tract infection (24%), pneumonia (19%), and occult bacteraemia (18%). One child died and seven had persisting neurological impairment. Five serotypes caused 83% of disease and 92% of the serotypes are included in the seven valent conjugate vaccines which are undergoing trials. Conclusions - These data suggest that S pneumoniae infection is associated with a low case fatality rate but substantial morbidity in the UK. |
| first_indexed | 2024-03-07T03:11:39Z |
| format | Journal article |
| id | oxford-uuid:b465e73e-2603-4e0b-a7c4-de69634b15bf |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:11:39Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:b465e73e-2603-4e0b-a7c4-de69634b15bf2022-03-27T04:25:53ZOutcome of invasive pneumococcal disease: a UK based studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b465e73e-2603-4e0b-a7c4-de69634b15bfEnglishSymplectic Elements at Oxford2000Shackley, FKnox, KMorris, JCrook, DGriffiths, DMayon-White, RGeorge, RWillocks, LMoxon, EGr, OMethods - The records of 106 children aged less than 5 years with invasive disease caused by Streptococcus pneumoniae were reviewed. Results - The clinical manifestations were meningitis (37%), upper respiratory tract infection (24%), pneumonia (19%), and occult bacteraemia (18%). One child died and seven had persisting neurological impairment. Five serotypes caused 83% of disease and 92% of the serotypes are included in the seven valent conjugate vaccines which are undergoing trials. Conclusions - These data suggest that S pneumoniae infection is associated with a low case fatality rate but substantial morbidity in the UK. |
| spellingShingle | Shackley, F Knox, K Morris, J Crook, D Griffiths, D Mayon-White, R George, R Willocks, L Moxon, E Gr, O Outcome of invasive pneumococcal disease: a UK based study |
| title | Outcome of invasive pneumococcal disease: a UK based study |
| title_full | Outcome of invasive pneumococcal disease: a UK based study |
| title_fullStr | Outcome of invasive pneumococcal disease: a UK based study |
| title_full_unstemmed | Outcome of invasive pneumococcal disease: a UK based study |
| title_short | Outcome of invasive pneumococcal disease: a UK based study |
| title_sort | outcome of invasive pneumococcal disease a uk based study |
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