A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors

অনুরূপ উপাদানগুলি

• A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors.
  অনুযায়ী: Leijen, S, অন্যান্য
  প্রকাশিত: (2011)
• DOC-MEK: A double-blind randomized phase II trial of docetaxel with or without selumetinib (AZD6244; ARRY-142886) in wt BRAF advanced melanoma
  অনুযায়ী: Gupta, A, অন্যান্য
  প্রকাশিত: (2013)
• AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study
  অনুযায়ী: Dummer, R, অন্যান্য
  প্রকাশিত: (2008)
• MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib
  অনুযায়ী: Takahashi, O, অন্যান্য
  প্রকাশিত: (2009)
• Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma.
  অনুযায়ী: Kirkwood, J, অন্যান্য
  প্রকাশিত: (2012)