Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort

We aimed to investigate the genetic associations of neuropathic pain in a deeply phenotyped cohort. Participants with neuropathic pain were cases and compared with those exposed to injury or disease but without neuropathic pain as control subjects. Diabetic polyneuropathy was the most common aetiolo...

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Bibliografiske detaljer
Main Authors:	Akerlund, M, Baskozos, G, Li, W, Themistocleous, AC, Pascal, MMV, Rayner, W, Comini, M, John, J, van Zuydam, N, McCarthy, MI, Lyssenko, V, Bennett, DL
Format:	Journal article
Sprog:	English
Udgivet:	Lippincott, Williams & Wilkins 2024

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Somatosensory and psychological phenotypes associated with neuropathic pain in entrapment neuropathy
af: Matesanz, L, et al.
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Using stratified medicine to understand, diagnose, and treat neuropathic pain
af: Themistocleous, AC, et al.
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Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy
af: Vale, T, et al.
Udgivet: (2017)

Investigating genotype–phenotype relationship of extreme neuropathic pain disorders in a UK national cohort
af: Themistocleous, AC, et al.
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Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients
af: Sieberg, C, et al.
Udgivet: (2018)

Epidemiology of neuropathic pain: an analysis of prevalence and associated factors in UK Biobank
af: Baskozos, G, et al.
Udgivet: (2023)

Classification of painful or painless diabetic peripheral neuropathy and identification of the most powerful predictors using machine learning models in large cross-sectional cohorts
af: Baskozos, G, et al.
Udgivet: (2022)

Cohort profile: DOLORisk Dundee: a longitudinal study of chronic neuropathic pain
af: Hébert, HL, et al.
Udgivet: (2021)

Systemic inflammatory markers in neuropathic pain, nerve injury and recovery
af: Sandy-Hindmarch, O, et al.
Udgivet: (2021)

The relationship of nerve fibre pathology to sensory function in entrapment neuropathy
af: Schmid, A, et al.
Udgivet: (2014)

Late onset hereditary sensory and autonomic neuropathy with cognitive impairment associated with Y163X prion mutation.
af: Themistocleous, A, et al.
Udgivet: (2014)

HIV-associated sensory neuropathy: Still a problem in the post-stavudine era?
af: Cherry, C, et al.
Udgivet: (2012)

An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
af: Clark, A, et al.
Udgivet: (2021)

Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations
af: Vollert, J, et al.
Udgivet: (2017)

The clinical approach to small fibre neuropathy and painful channelopathy.
af: Themistocleous, A, et al.
Udgivet: (2014)

Eleven neurology-related proteins measured in serum are positively correlated to the severity of diabetic neuropathy
af: Bäckryd, E, et al.
Udgivet: (2024)

DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain
af: Pascal, M, et al.
Udgivet: (2018)

Deep RNA-seq of male and female murine sensory neuron subtypes after nerve injury
af: Barry, AM, et al.
Udgivet: (2023)

Using an engineered GluCl channel to silence sensory neurons and treat neuropathic pain at the source
af: Weir, G, et al.
Udgivet: (2017)

The Pain in Neuropathy Study (PiNS)
af: Themistocleous, A, et al.
Udgivet: (2016)

Disturbances in affective touch in hereditary sensory and autonomic neuropathy type III.
af: Macefield, V, et al.
Udgivet: (2014)

Neuroinflammation and the generation of neuropathic pain.
af: Ellis, A, et al.
Udgivet: (2013)

Utilising clinical parameters to improve the selection of nerve biopsy candidates
af: Kopanidis, P, et al.
Udgivet: (2023)

Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations
af: Sleigh, J, et al.
Udgivet: (2017)

Neuropathic pain
af: Colloca, L, et al.
Udgivet: (2017)

Think deeply about the future
af: Abd Razak, Dzulkifli
Udgivet: (2009)

Rare Nav1.7 variants associated with painful diabetic peripheral neuropathy
af: Blesneac, I, et al.
Udgivet: (2017)

The local molecular signature of human peripheral neuropathic pain
af: Sandy-Hindmarch, OP, et al.
Udgivet: (2024)

Hepatitis C seropositivity is not a risk factor for sensory neuropathy among patients with HIV
af: Cherry, C.L., et al.
Udgivet: (2010)

Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy
af: Pereira, Jose H., et al.
Udgivet: (2018)

Measurement of deeply virtual Compton scattering at HERA
af: Adloff, C, et al.
Udgivet: (2001)

Sensory, psychological, and metabolic dysfunction in HIV-associated peripheral neuropathy: A cross-sectional deep profiling study.
af: Phillips, T, et al.
Udgivet: (2014)

Color transparency in deeply inelastic diffraction
af: Hautmann, F, et al.
Udgivet: (2001)

Color transparency in deeply inelastic diffraction
af: Hautmann, F, et al.
Udgivet: (2001)

Oscillatory neural representations in the sensory thalamus predict neuropathic pain relief by deep brain stimulation
af: Huang, Y, et al.
Udgivet: (2017)

Pathogenic mechanisms in inflammatory and paraproteinaemic peripheral neuropathies.
af: Rinaldi, S, et al.
Udgivet: (2014)

Sensory profiles are comparable in patients with distal and proximal entrapment neuropathies, while the pain experience differs
af: Tampin, B, et al.
Udgivet: (2018)

The role of the immune system in the generation of neuropathic pain.
af: Calvo, M, et al.
Udgivet: (2012)

THE SPINAL NERVE TRANSECTION MODEL OF NEUROPATHIC PAIN IS ASSOCIATED WITH ALTERATIONS OF THE MOLECULAR ORGANISATION OF THE NODAL REGIONS OF MYELINATED SENSORY AXONS WITHIN THE DORSAL ROOT
af: Calvo, M, et al.
Udgivet: (2013)

Nerve pathology and neuropathic pain after whiplash: A systematic review and meta-analysis
af: Fundaun, J, et al.
Udgivet: (2022)