The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis
Predictive coding potentially provides an explanatory model for understanding the neurocognitive mechanisms of psychosis. It proposes that cognitive processes, such as perception and inference, are implemented by a hierarchical system, with the influence of each level being a function of the estimat...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Elsevier
2020
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| _version_ | 1797108198837059584 |
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| author | Haarsma, J Kok, P Browning, M |
| author_facet | Haarsma, J Kok, P Browning, M |
| author_sort | Haarsma, J |
| collection | OXFORD |
| description | Predictive coding potentially provides an explanatory model for understanding the neurocognitive mechanisms of psychosis. It proposes that cognitive processes, such as perception and inference, are implemented by a hierarchical system, with the influence of each level being a function of the estimated precision of beliefs at that level. However, predictive coding models of psychosis are insufficiently constrained—any phenomenon can be explained in multiple ways by postulating different changes to precision at different levels of processing. One reason for the lack of constraint in these models is that the core processes are thought to be implemented by the function of specific cortical layers, and the technology to measure layer specific neural activity in humans has until recently been lacking. As a result, our ability to constrain the models with empirical data has been limited. In this review we provide a brief overview of predictive processing models of psychosis and then describe the potential for newly developed, layer specific neuroimaging techniques to test and thus constrain these models. We conclude by discussing the most promising avenues for this research as well as the technical and conceptual challenges which may limit its application. |
| first_indexed | 2024-03-07T07:26:05Z |
| format | Journal article |
| id | oxford-uuid:b47f4b95-6b8a-4d57-b254-bbfd95a1e06d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:26:05Z |
| publishDate | 2020 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:b47f4b95-6b8a-4d57-b254-bbfd95a1e06d2022-11-15T10:18:16ZThe promise of layer-specific neuroimaging for testing predictive coding theories of psychosisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b47f4b95-6b8a-4d57-b254-bbfd95a1e06dEnglishSymplectic ElementsElsevier2020Haarsma, JKok, PBrowning, MPredictive coding potentially provides an explanatory model for understanding the neurocognitive mechanisms of psychosis. It proposes that cognitive processes, such as perception and inference, are implemented by a hierarchical system, with the influence of each level being a function of the estimated precision of beliefs at that level. However, predictive coding models of psychosis are insufficiently constrained—any phenomenon can be explained in multiple ways by postulating different changes to precision at different levels of processing. One reason for the lack of constraint in these models is that the core processes are thought to be implemented by the function of specific cortical layers, and the technology to measure layer specific neural activity in humans has until recently been lacking. As a result, our ability to constrain the models with empirical data has been limited. In this review we provide a brief overview of predictive processing models of psychosis and then describe the potential for newly developed, layer specific neuroimaging techniques to test and thus constrain these models. We conclude by discussing the most promising avenues for this research as well as the technical and conceptual challenges which may limit its application. |
| spellingShingle | Haarsma, J Kok, P Browning, M The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis |
| title | The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis |
| title_full | The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis |
| title_fullStr | The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis |
| title_full_unstemmed | The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis |
| title_short | The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis |
| title_sort | promise of layer specific neuroimaging for testing predictive coding theories of psychosis |
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