ABPP-HT - high-throughput activity-based profiling of deubiquitylating enzyme inhibitors in a cellular context
The potency and selectivity of a small molecule inhibitor are key parameters to assess during the early stages of drug discovery. In particular, it is very informative for characterizing compounds in a relevant cellular context in order to reveal potential off-target effects and drug efficacy. Activ...
| Autors principals: | , , , , |
|---|---|
| Format: | Journal article |
| Idioma: | English |
| Publicat: |
Frontiers Media
2021
|