Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription

Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription

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The estrogen receptor α (ERα) controls cell proliferation and tumorigenesis by recruiting various cofactors to estrogen response elements (EREs) to control gene transcription. A deeper understanding of these transcriptional mechanisms may uncover therapeutic targets for ERα-dependent cancers. We sho...

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Main Authors:	Nagarajan, S, Hossan, T, Alawi, M, Najafova, Z, Indenbirken, D, Bedi, U, Taipaleenmäki, H, Ben-Batalla, I, Scheller, M, Loges, S, Knapp, S, Hesse, E, Chiang, C, Grundhoff, A, Johnsen, SA
Format:	Journal article
Language:	English
Published:	Elsevier 2014

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