Structural insights into the broad-spectrum antiviral target endoplasmic reticulum alpha-glucosidase II

Targeting the host-cell endoplasmic reticulum quality control (ERQC) pathway is an effective broad-spectrum antiviral strategy. The two ER resident α-glucosidases whose sequential action permits entry in this pathway are the targets of glucomimetic inhibitors. Knowledge of the molecular details of t...

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Detalhes bibliográficos
Principais autores: Zitzmann, N, Caputo, AT, Alonzi, DS, Kiappes, JL, Struwe, WB, Cross, A, Basu, S, Darlot, B, Roversi, P
Outros Autores: Hilgenfeld, R
Formato: Book section
Idioma:English
Publicado em: Springer 2018

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