Immune escape variants of H9N2 influenza viruses containing deletions at the hemagglutinin receptor binding site retain fitness in vivo and display enhanced zoonotic characteristics
H9N2 avian influenza viruses are enzootic in poultry across Asia and North Africa, where they pose a threat to human health as both zoonotic agents and potential pandemic candidates. Poultry vaccination against H9N2 viruses has been employed in many regions; however, vaccine effectiveness is frequen...
Main Authors: | Peacock, TP, Benton, DJ, James, J, Sadeyen, J-R, Chang, P, Sealy, JE, Bryant, JE, Martin, SR, Shelton, H, Barclay, WS, Iqbal, M |
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Other Authors: | García-Sastre, A |
Format: | Journal article |
Language: | English |
Published: |
American Society for Microbiology
2017
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