Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

Decysin-1 (ADAMDEC1) is an orphan ADAM-like metalloprotease with unknown biological function and a short domain structure. ADAMDEC1 mRNA has previously been demonstrated primarily in macrophages and mature dendritic cells. Here, we generated monoclonal antibodies (mAbs) against the mature ADAMDEC1 p...

書誌詳細
主要な著者:	Lund, J, Elimar Bitsch, A, Grønbech Rasch, M, Enoksson, M, Troeberg, L, Nagase, H, Loftager, M, Overgaard, M, Petersen, H
フォーマット:	Journal article
言語:	English
出版事項:	Taylor and Francis 2017

類似資料

Evidence for Restricted Reactivity of ADAMDEC1 with Protein Substrates and Endogenous Inhibitors.
著者:: Lund, J, 等
出版事項: (2015)

ADAMDEC1 accelerates GBM progression via activation of the MMP2-related pathway
著者:: Huimin Qi, 等
出版事項: (2022-09-01)

ADAMDEC1 promotes the malignant progression of cholangiocarcinoma by regulating NF-κB signaling pathway
著者:: Shuo Zhou, 等
出版事項: (2025-01-01)

ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells
著者:: Ana Jimenez-Pascual, 等
出版事項: (2020-01-01)

Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
著者:: Yamamoto, K, 等
出版事項: (2014)

Disintegrins from Hematophagous Sources
著者:: Ivo M. B. Francischetti, 等
出版事項: (2012-04-01)

Snake Venom Disintegrins and Cell Migration
著者:: Heloisa S. Selistre-de-Araujo, 等
出版事項: (2010-10-01)

Proteolytic fragments of tenascin-C promote cartilage degradation
著者:: Sofat, N, 等
出版事項: (2010)

Trypanosoma cruzy proteolytic activities after immunoprecipitation with the monoclonal antibody H1A10
著者:: Eloise Cedro Fernandes
出版事項: (2018-01-01)

Aggrecan breakdown in cartilage induced by proteolytic fragments of fibronectin: implications in osteoarthritis
著者:: Nagase, H
出版事項: (2009)

The Role of Snake Venom Disintegrins in Angiogenesis
著者:: Patricia Bianca Clissa, 等
出版事項: (2024-03-01)

Recombinant and Chimeric Disintegrins in Preclinical Research
著者:: Victor David, 等
出版事項: (2018-08-01)

Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases
著者:: D. Dreymueller, 等
出版事項: (2017-01-01)

Voltage-Gated Calcium Channel alpha(2)delta Subunits in Lipid Rafts: The Importance of Proteolytic Cleavage Into alpha(2) and delta
著者:: Kadurin, I, 等
出版事項: (2012)

Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis
著者:: Boeddha, NP, 等
出版事項: (2021)

Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody[S]
著者:: Krista M. Schroeder, 等
出版事項: (2015-11-01)

Detectable A Disintegrin and Metalloproteinase With Thrombospondin Motifs-1 in Serum Is Associated With Adverse Outcome in Pediatric Sepsis
著者:: Navin P. Boeddha, MD, PhD, 等
出版事項: (2021-11-01)

Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B
著者:: Yongfeng Fan, 等
出版事項: (2015-08-01)

Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate.
著者:: Lauer-Fields, J, 等
出版事項: (2008)

A Disintegrin and Metalloprotease 33 polymorphisms and lung function decline in the general population
著者:: Cleo. C. van Diemen, 等
出版事項: (2006-12-01)

Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity
著者:: Gossens, K, 等
出版事項: (2010)

Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity.
著者:: Gossens, K, 等
出版事項: (2010)

A DISINTEGRIN AND METALLOPROTEASE 17 IN THE CARDIOVASCULAR AND CENTRAL NERVOUS SYSTEMS
著者:: Jiaxi Xu, 等
出版事項: (2016-10-01)

A Disintegrin and Metalloprotease (ADAM): Historical Overview of Their Functions
著者:: Nives Giebeler, 等
出版事項: (2016-04-01)

ADAM-15 Disintegrin-Like Domain Structure and Function
著者:: Dong Lu, 等
出版事項: (2010-10-01)

A Disintegrin and Metalloproteinase—Control Elements in Infectious Diseases
著者:: Ahmad Aljohmani, 等
出版事項: (2020-12-01)

MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms
著者:: Gifford, V, 等
出版事項: (2019)

Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration
著者:: Gregor Bieri, 等
出版事項: (2018-12-01)

THE TYPE III 8-10 REPEATS OF FIBRONECTIN INDUCE AGGRECANASE ACTIVITY VIA ALPHA5BETA1 INTEGRIN AND THE TYPE III 13-14 REPEATS ACT VIA TLR 4 RECEPTORS
著者:: Sofat, N, 等
出版事項: (2009)

The type III 8-10 repeats of fibronectin induce aggrecanase activity via alpha(5)beta(1) integrin and type III 13-14 repeats act via TLR 4 receptors
著者:: Sofat, N, 等
出版事項: (2009)

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
著者:: Kashiwagi, M, 等
出版事項: (2004)

ADAM15 Disintegrin Is Associated with Aggressive Prostate and Breast Cancer Disease
著者:: Rainer Kuefer, 等
出版事項: (2006-04-01)

Snake venom disintegrins update: insights about new findings
著者:: Gabriela de Oliveira Almeida, 等
出版事項: (2023-09-01)

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.
著者:: Gendron, C, 等
出版事項: (2007)

Alternagin-C, a disintegrin-like protein from the venom of Bothrops alternatus, modulates a2ß1 integrin-mediated cell adhesion, migration and proliferation
著者:: Selistre-de-Araujo H.S., 等
出版事項: (2005-01-01)

Monitoring metalloproteinase activity using synthetic fluorogenic substrates.
著者:: Troeberg, L, 等
出版事項: (2004)

Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage
著者:: Troeberg, L, 等
出版事項: (2009)

Proteases involved in cartilage matrix degradation in osteoarthritis.
著者:: Troeberg, L, 等
出版事項: (2012)

Measurement of matrix metalloproteinase activities in the medium of cultured synoviocytes using zymography.
著者:: Troeberg, L, 等
出版事項: (2003)

Zymography of metalloproteinases.
著者:: Troeberg, L, 等
出版事項: (2004)