Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

Decysin-1 (ADAMDEC1) is an orphan ADAM-like metalloprotease with unknown biological function and a short domain structure. ADAMDEC1 mRNA has previously been demonstrated primarily in macrophages and mature dendritic cells. Here, we generated monoclonal antibodies (mAbs) against the mature ADAMDEC1 p...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Lund, J, Elimar Bitsch, A, Grønbech Rasch, M, Enoksson, M, Troeberg, L, Nagase, H, Loftager, M, Overgaard, M, Petersen, H
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Taylor and Francis 2017