Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia

Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia

BACKGROUND: Cell-free foetal haemoglobin (HbF) has been shown to play a role in the pathology of preeclampsia (PE). In the present study, we aimed to further characterize the harmful effects of extracellular free haemoglobin (Hb) on the placenta. In particular, we investigated whether cell-free Hb a...

書誌詳細
主要な著者:	Cronqvist, T, Saljé, K, Familari, M, Guller, S, Schneider, H, Gardiner, C, Sargent, I, Redman, C, Mörgelin, M, Åkerström, B, Gram, M, Hansson, SR
フォーマット:	Journal article
言語:	English
出版事項:	Public Library of Science 2014

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