A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG mediated protection in a murine model of tuberculosis
<h4>Background</h4> <p>In the absence of a validated animal model and/or an immune correlate which predict vaccine-mediated protection, large-scale clinical trials are currently the only option to prove efficacy of new tuberculosis candidate vaccines. Tools to facilitate testing of...
Main Authors: | McShane, H, Tanner, R, Zelmer, A, Stylianou, E, Damelang, T, Morris, S, Izzo, A, Williams, A, Sharpe, S, Pepponi, I, Walker, B, Hokey, D, Brennan, M, Fletcher, H |
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Format: | Journal article |
Published: |
BioMed Central
2016
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