Structural basis for proton coupled cystine transport by cystinosin
<p>Amino acid transporters play a key role controlling the flow of nutrients across the lysosomal membrane and regulating metabolism in the cell. Mutations in the gene encoding the transporter cystinosin result in cystinosis, an autosomal recessive metabolic disorder characterised by the accum...
Main Authors: | Löbel, M, Salphati, SP, El Omari, K, Wagner, A, Tucker, SJ, Parker, JL, Newstead, S |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
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