Malaria is not responsible for the selection of TCR beta-subunit variable gene haplotypes in The Gambia.
Previous work has shown that a single haplotype of the T-cell antigen receptor beta-subunit (TCRB) locus is predominant in African populations. This is likely to be due to selection pressure for gene(s) that protect children against disease. This study has tested the hypothesis that malaria is the r...
Main Authors: | Donaldson, I, Shefta, J, Hill, A, Boylston, A |
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Format: | Journal article |
Language: | English |
Published: |
2002
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