Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation
The classical model of hematopoiesis proposes a hierarchy in which a small number of multipotent hematopoietic stem cells (HSCs) maintain all blood lineages by giving rise to progeny that pass through discrete progenitor stages. At each stage, lineage differentiation potential is restricted, coupled...
Hoofdauteurs: | Psaila, B, Mead, A |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
American Society of Hematology
2019
|
Gelijkaardige items
-
Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways
door: Psaila, B, et al.
Gepubliceerd in: (2016) -
MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte–erythroid progenitor lineage commitment
door: Zhang, L., et al.
Gepubliceerd in: (2014) -
A single-cell approach to unraveling abnormal megakaryocyte differentiation and function in myelofibrosis
door: Psaila, B, et al.
Gepubliceerd in: (2017) -
ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.
door: Schuh, A, et al.
Gepubliceerd in: (2005) -
Single-cell analyses reveal megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets
door: Psaila, B, et al.
Gepubliceerd in: (2020)