An inhibitor of complement C5 provides structural insights into activation
The complement system is a crucial part of innate immune defenses against invading pathogens. The blood-meal of the tick Rhipicephalus pulchellus lasts for days, and the tick must therefore rely on inhibitors to counter complement activation. We have identified a class of inhibitors from tick saliva...
Hlavní autoři: | Reichhardt, M, Johnson, S, Tang, T, Morgan, T, Tebeka, N, Popitsch, N, Deme, J, Jore, M, Lea, S |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
National Academy of Sciences
2019
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