An inhibitor of complement C5 provides structural insights into activation

The complement system is a crucial part of innate immune defenses against invading pathogens. The blood-meal of the tick Rhipicephalus pulchellus lasts for days, and the tick must therefore rely on inhibitors to counter complement activation. We have identified a class of inhibitors from tick saliva...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Reichhardt, M, Johnson, S, Tang, T, Morgan, T, Tebeka, N, Popitsch, N, Deme, J, Jore, M, Lea, S
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: National Academy of Sciences 2019