RAB11FIP5 expression and altered natural killer cell function are associated with induction of HIV broadly neutralizing antibody responses

RAB11FIP5 expression and altered natural killer cell function are associated with induction of HIV broadly neutralizing antibody responses

HIV-1 broadly neutralizing antibodies (bnAbs) are difficult to induce with vaccines but are generated in ∼50% of HIV-1-infected individuals. Understanding the molecular mechanisms of host control of bnAb induction is critical to vaccine design. Here, we performed a transcriptome analysis of blood mo...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Bradley, T, Peppa, D, Pedroza-Pacheco, I, Borrow, P, al., E
Formatua:	Journal article
Argitaratua:	Cell Press 2018

Antzeko izenburuak

RAB11FIP5-deficient mice exhibit cytokine-related transcriptomic signatures
nork: Li, D, et al.
Argitaratua: (2020)

The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development
nork: Cayla E. Jewett, et al.
Argitaratua: (2020-10-01)

Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection
nork: Dimitra Peppa, et al.
Argitaratua: (2018-03-01)

Acquisition of Rab11 and Rab11-Fip2-A novel strategy for Chlamydia pneumoniae early survival.
nork: Katja Mölleken, et al.
Argitaratua: (2017-08-01)

Rab11-FIP3 is a cell cycle-regulated phosphoprotein
nork: Collins Louise L, et al.
Argitaratua: (2012-03-01)

Adaptive reconfiguration of natural killer cells in HIV-1 infection
nork: Peppa, D, et al.
Argitaratua: (2018)

Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex.
nork: Mingli Qi, et al.
Argitaratua: (2013-01-01)

Rabs, Rips, FIPs, and Endocytic Membrane Traffic
nork: Rytis Prekeris
Argitaratua: (2003-01-01)

Viral Vectors for the Induction of Broadly Neutralizing Antibodies against HIV
nork: Sarah Wilmschen, et al.
Argitaratua: (2019-09-01)

Correction: The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion
Argitaratua: (2014-01-01)

Correction: The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion.
Argitaratua: (2014-01-01)

Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies
nork: Borrow, P, et al.
Argitaratua: (2017)

Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies
nork: Garnett Kelsoe, et al.
Argitaratua: (2013-12-01)

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies
nork: Haynes, BF, et al.
Argitaratua: (2022)

Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies
nork: Moody, M, et al.
Argitaratua: (2016)

P19-11. Generation of virus-like particles expressing different HIV-1 glycoproteins for induction of broadly neutralizing antibodies
nork: Buonaguro L, et al.
Argitaratua: (2009-10-01)

The expanding array of HIV broadly neutralizing antibodies
nork: Laura E. McCoy
Argitaratua: (2018-10-01)

Broadly Neutralizing Antibodies for HIV-1 Prevention
nork: Stephen R. Walsh, et al.
Argitaratua: (2021-07-01)

The potential of broadly neutralizing antibodies for HIV prevention
nork: Huub C. Gelderblom, et al.
Argitaratua: (2024-05-01)

Tumor susceptibility gene 101 (TSG101) is a novel binding-partner for the class II Rab11-FIPs.
nork: Conor P Horgan, et al.
Argitaratua: (2012-01-01)

Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers
nork: Elise Landais, et al.
Argitaratua: (2018-09-01)

Rab11-FIP1/RCP Functions as a Major Signalling Hub in the Oncogenic Roles of Mutant p53 in Cancer
nork: Yannick von Grabowiecki, et al.
Argitaratua: (2021-12-01)

RAB11FIP1: An Indicator for Tumor Immune Microenvironment and Prognosis of Lung Adenocarcinoma from a Comprehensive Analysis of Bioinformatics
nork: Wenyi Zhang, et al.
Argitaratua: (2021-10-01)

B cell engineering in vivo: Accelerating induction of broadly neutralizing antibodies against HIV-1 infection
nork: Caijun Sun, et al.
Argitaratua: (2023-01-01)

Broadly neutralizing antibodies for HIV-1: efficacies, challenges and opportunities
nork: Yubin Liu, et al.
Argitaratua: (2020-01-01)

HIV-1 cell-to-cell transmission and broadly neutralizing antibodies
nork: Jérémy Dufloo, et al.
Argitaratua: (2018-07-01)

Elimination of HIV-1-infected cells by broadly neutralizing antibodies
nork: Timothée Bruel, et al.
Argitaratua: (2016-03-01)

Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic
nork: David A. Spencer, et al.
Argitaratua: (2021-05-01)

Development of an anti-HIV vaccine eliciting broadly neutralizing antibodies
nork: Yousuf Ahmed, et al.
Argitaratua: (2017-09-01)

Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques.
nork: Yvonne Rosenberg, et al.
Argitaratua: (2015-01-01)

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.
nork: Laura E McCoy, et al.
Argitaratua: (2015-08-01)

Neutralizing the threat: harnessing broadly neutralizing antibodies against HIV-1 for treatment and prevention
nork: Juan C Becerra, et al.
Argitaratua: (2024-07-01)

Predicting neutralization susceptibility to combination HIV-1 monoclonal broadly neutralizing antibody regimens.
nork: Brian D Williamson, et al.
Argitaratua: (2024-01-01)

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.
nork: Kong, R, et al.
Argitaratua: (2012)

Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
nork: Rory Henderson, et al.
Argitaratua: (2024-11-01)

Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV
nork: Sarah B. Lloyd, et al.
Argitaratua: (2017-11-01)

Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention.
nork: Bryan T Mayer, et al.
Argitaratua: (2022-04-01)

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
nork: Julie Prigent, et al.
Argitaratua: (2018-05-01)

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data
nork: Ferguson, Andrew L., et al.
Argitaratua: (2014)

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
nork: Sok, Devin, et al.
Argitaratua: (2014)