RAB11FIP5 expression and altered natural killer cell function are associated with induction of HIV broadly neutralizing antibody responses

RAB11FIP5 expression and altered natural killer cell function are associated with induction of HIV broadly neutralizing antibody responses

HIV-1 broadly neutralizing antibodies (bnAbs) are difficult to induce with vaccines but are generated in ∼50% of HIV-1-infected individuals. Understanding the molecular mechanisms of host control of bnAb induction is critical to vaccine design. Here, we performed a transcriptome analysis of blood mo...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Bradley, T, Peppa, D, Pedroza-Pacheco, I, Borrow, P, al., E
स्वरूप:	Journal article
प्रकाशित:	Cell Press 2018

समान संसाधन

RAB11FIP5-deficient mice exhibit cytokine-related transcriptomic signatures
द्वारा: Li, D, और अन्य
प्रकाशित: (2020)

The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development
द्वारा: Cayla E. Jewett, और अन्य
प्रकाशित: (2020-10-01)

Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection
द्वारा: Dimitra Peppa, और अन्य
प्रकाशित: (2018-03-01)

Acquisition of Rab11 and Rab11-Fip2-A novel strategy for Chlamydia pneumoniae early survival.
द्वारा: Katja Mölleken, और अन्य
प्रकाशित: (2017-08-01)

Rab11-FIP3 is a cell cycle-regulated phosphoprotein
द्वारा: Collins Louise L, और अन्य
प्रकाशित: (2012-03-01)

Adaptive reconfiguration of natural killer cells in HIV-1 infection
द्वारा: Peppa, D, और अन्य
प्रकाशित: (2018)

Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex.
द्वारा: Mingli Qi, और अन्य
प्रकाशित: (2013-01-01)

Rabs, Rips, FIPs, and Endocytic Membrane Traffic
द्वारा: Rytis Prekeris
प्रकाशित: (2003-01-01)

Viral Vectors for the Induction of Broadly Neutralizing Antibodies against HIV
द्वारा: Sarah Wilmschen, और अन्य
प्रकाशित: (2019-09-01)

Correction: The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion
प्रकाशित: (2014-01-01)

Correction: The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion.
प्रकाशित: (2014-01-01)

Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies
द्वारा: Borrow, P, और अन्य
प्रकाशित: (2017)

Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies
द्वारा: Garnett Kelsoe, और अन्य
प्रकाशित: (2013-12-01)

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies
द्वारा: Haynes, BF, और अन्य
प्रकाशित: (2022)

Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies
द्वारा: Moody, M, और अन्य
प्रकाशित: (2016)

P19-11. Generation of virus-like particles expressing different HIV-1 glycoproteins for induction of broadly neutralizing antibodies
द्वारा: Buonaguro L, और अन्य
प्रकाशित: (2009-10-01)

The expanding array of HIV broadly neutralizing antibodies
द्वारा: Laura E. McCoy
प्रकाशित: (2018-10-01)

Broadly Neutralizing Antibodies for HIV-1 Prevention
द्वारा: Stephen R. Walsh, और अन्य
प्रकाशित: (2021-07-01)

The potential of broadly neutralizing antibodies for HIV prevention
द्वारा: Huub C. Gelderblom, और अन्य
प्रकाशित: (2024-05-01)

Tumor susceptibility gene 101 (TSG101) is a novel binding-partner for the class II Rab11-FIPs.
द्वारा: Conor P Horgan, और अन्य
प्रकाशित: (2012-01-01)

Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers
द्वारा: Elise Landais, और अन्य
प्रकाशित: (2018-09-01)

Rab11-FIP1/RCP Functions as a Major Signalling Hub in the Oncogenic Roles of Mutant p53 in Cancer
द्वारा: Yannick von Grabowiecki, और अन्य
प्रकाशित: (2021-12-01)

RAB11FIP1: An Indicator for Tumor Immune Microenvironment and Prognosis of Lung Adenocarcinoma from a Comprehensive Analysis of Bioinformatics
द्वारा: Wenyi Zhang, और अन्य
प्रकाशित: (2021-10-01)

B cell engineering in vivo: Accelerating induction of broadly neutralizing antibodies against HIV-1 infection
द्वारा: Caijun Sun, और अन्य
प्रकाशित: (2023-01-01)

Broadly neutralizing antibodies for HIV-1: efficacies, challenges and opportunities
द्वारा: Yubin Liu, और अन्य
प्रकाशित: (2020-01-01)

HIV-1 cell-to-cell transmission and broadly neutralizing antibodies
द्वारा: Jérémy Dufloo, और अन्य
प्रकाशित: (2018-07-01)

Elimination of HIV-1-infected cells by broadly neutralizing antibodies
द्वारा: Timothée Bruel, और अन्य
प्रकाशित: (2016-03-01)

Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic
द्वारा: David A. Spencer, और अन्य
प्रकाशित: (2021-05-01)

Development of an anti-HIV vaccine eliciting broadly neutralizing antibodies
द्वारा: Yousuf Ahmed, और अन्य
प्रकाशित: (2017-09-01)

Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques.
द्वारा: Yvonne Rosenberg, और अन्य
प्रकाशित: (2015-01-01)

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.
द्वारा: Laura E McCoy, और अन्य
प्रकाशित: (2015-08-01)

Neutralizing the threat: harnessing broadly neutralizing antibodies against HIV-1 for treatment and prevention
द्वारा: Juan C Becerra, और अन्य
प्रकाशित: (2024-07-01)

Predicting neutralization susceptibility to combination HIV-1 monoclonal broadly neutralizing antibody regimens.
द्वारा: Brian D Williamson, और अन्य
प्रकाशित: (2024-01-01)

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.
द्वारा: Kong, R, और अन्य
प्रकाशित: (2012)

Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
द्वारा: Rory Henderson, और अन्य
प्रकाशित: (2024-11-01)

Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV
द्वारा: Sarah B. Lloyd, और अन्य
प्रकाशित: (2017-11-01)

Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention.
द्वारा: Bryan T Mayer, और अन्य
प्रकाशित: (2022-04-01)

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
द्वारा: Julie Prigent, और अन्य
प्रकाशित: (2018-05-01)

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data
द्वारा: Ferguson, Andrew L., और अन्य
प्रकाशित: (2014)

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
द्वारा: Sok, Devin, और अन्य
प्रकाशित: (2014)