RAB11FIP5 expression and altered natural killer cell function are associated with induction of HIV broadly neutralizing antibody responses

HIV-1 broadly neutralizing antibodies (bnAbs) are difficult to induce with vaccines but are generated in ∼50% of HIV-1-infected individuals. Understanding the molecular mechanisms of host control of bnAb induction is critical to vaccine design. Here, we performed a transcriptome analysis of blood mo...

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Détails bibliographiques
Auteurs principaux: Bradley, T, Peppa, D, Pedroza-Pacheco, I, Borrow, P, al., E
Format: Journal article
Publié: Cell Press 2018