Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory.

Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory.

Mice rendered B cell deficient by targeted disruption of the immunoglobulin mu chain gene (IgM-/- mice) were used to analyze the role of antibodies and B cells in viral infections; homozygous IgM-/- mice were bred in a way to avoid transmission of maternal antibodies. After infection with vesicular...

Полное описание

Библиографические подробности
Главные авторы:	Bründler, M, Aichele, P, Bachmann, M, Kitamura, D, Rajewsky, K, Zinkernagel, R
Формат:	Journal article
Язык:	English
Опубликовано:	1996

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