Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory.

Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory.

Mice rendered B cell deficient by targeted disruption of the immunoglobulin mu chain gene (IgM-/- mice) were used to analyze the role of antibodies and B cells in viral infections; homozygous IgM-/- mice were bred in a way to avoid transmission of maternal antibodies. After infection with vesicular...

Podrobná bibliografie
Hlavní autoři:	Bründler, M, Aichele, P, Bachmann, M, Kitamura, D, Rajewsky, K, Zinkernagel, R
Médium:	Journal article
Jazyk:	English
Vydáno:	1996

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