Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

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Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP), we genotyped ∼50,000 SNPs in up to 87,736 individuals of European ancestry and combined th...

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Bibliographic Details
Main Authors: Tragante, V, Barnes, MR, Ganesh, S, Lanktree, M, Guo, W, Franceschini, N, Smith, E, Johnson, T, Holmes, M, Padmanabhan, S, Karczewski, K, Almoguera, B, Barnard, J, Baumert, J, Chang, Y, Elbers, C, Farrall, M, Fischer, M, Gaunt, T, Gho, J, Gieger, C, Goel, A
Format: Journal article
Published: 2014

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