Intermolecular alkene and alkyne hydroacylation with beta-S-substituted aldehydes: mechanistic insight into the role of a hemilabile P-O-P ligand.

Intermolecular alkene and alkyne hydroacylation with beta-S-substituted aldehydes: mechanistic insight into the role of a hemilabile P-O-P ligand.

A straightforward to assemble catalytic system for the intermolecular hydroacylation reaction of beta-S-substituted aldehydes with activated and unactivated alkenes and alkynes is reported. These catalysts promote the hydroacylation reaction between beta-S-substituted aldehydes and challenging subst...

书目详细资料
Main Authors:	Moxham, G, Randell-Sly, H, Brayshaw, S, Weller, A, Willis, M
格式:	Journal article
语言:	English
出版:	2008

相似书籍

A second-generation catalyst for intermolecular hydroacylation of alkenes and alkynes using beta-S-substituted aldehydes: the role of a hemilabile P-O-P ligand.
由: Moxham, G, et al.
出版: (2006)

Chelation-controlled intermolecular alkene and alkyne hydroacylation: the utility of beta-thioacetal aldehydes.
由: Willis, M, et al.
出版: (2005)

Rhodium-catalyzed intermolecular chelation controlled alkene and alkyne hydroacylation: synthetic scope of beta-S-substituted aldehyde substrates.
由: Willis, M, et al.
出版: (2006)

Controlling Selectivity in Intermolecular Alkene or Aldehyde Hydroacylation Reactions Catalyzed by {Rh(L-2)}(+) Fragments
由: Pawley, R, et al.
出版: (2010)

Traceless chelation-controlled rhodium-catalyzed intermolecular alkene and alkyne hydroacylation.
由: Hooper, J, et al.
出版: (2013)

Exploiting carbonyl groups to control intermolecular rhodium-catalyzed alkene and alkyne hydroacylation
由: Coxon, TJ, et al.
出版: (2017)

Exploring small bite-angle PNP and PCP ligands for the rhodium-catalysed intermolecular hydroacylation of b-s-substituted aldehydes with alkenes and alkynes
由: Pernik, I
出版: (2014)

Hydroacylation of Alkenes, Alkynes, and Allenes
由: Willis, M
出版: (2014)

Chelation-controlled intermolecular hydroacylation: direct addition of alkyl aldehydes to functionalized alkenes.
由: Willis, M, et al.
出版: (2004)

O-substituted alkyl aldehydes for rhodium-catalyzed intermolecular alkyne hydroacylation: the utility of methylthiomethyl ethers.
由: Parsons, SR, et al.
出版: (2011)

Transition metal catalyzed alkene and alkyne hydroacylation.
由: Willis, M
出版: (2010)

Intermolecular Alkyne Hydroacylation. Mechanistic Insight from the Isolation of the Vinyl Intermediate That Precedes Reductive Elimination
由: Pawley, R, et al.
出版: (2012)

Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes.
由: Osborne, J, et al.
出版: (2008)

Exploring Small Bite-Angle Ligands for the Rhodium-Catalyzed Intermolecular Hydroacylation of beta-S-Substituted Aldehydes with 1-Octene and 1-Octyne
由: Pernik, I, et al.
出版: (2012)

Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation
由: Moseley, D
出版: (2022)

α-amino aldehydes as readily available chiral aldehydes for Rh-catalyzed alkyne hydroacylation
由: Hooper, JF, et al.
出版: (2016)

α‐Amidoaldehydes as substrates in rhodium‐catalyzed intermolecular alkyne hydroacylation: The synthesis of α‐Amidoketones
由: Pal, R, et al.
出版: (2020)

Azine N-oxides as effective controlling groups for Rh-catalysed intermolecular alkyne hydroacylation
由: Moseley, DF, et al.
出版: (2021)

Rh(DPEPhos)-catalyzed alkyne hydroacylation using β-carbonyl-substituted aldehydes: mechanistic insight leads to low catalyst loadings that enables selective catalysis on gram-scale
由: Barwick-Silk, J, et al.
出版: (2018)

a-Amidoaldehydes as substrates in rhodium-catalyzed intermolecular alkyne hydroacylation: The synthesis of a-amidoketones
由: Pal, R, et al.
出版: (2020)

Rhodium-catalysed linear-selective alkyne hydroacylation.
由: Poingdestre, S, et al.
出版: (2012)

Mechanistic studies of rhodium-catalysed intermolecular hydroacylation
由: Barwick-Silk, J
出版: (2018)

Intermolecular rhodium catalyzed hydroacylation of allenes: the regioselective synthesis of beta,gamma-unsaturated ketones
由: Randell-Sly, H, et al.
出版: (2009)

Rhodium-catalysed intermolecular alkyne hydroacylation: the enantioselective synthesis of α- and β-substituted ketones by kinetic resolution.
由: González-Rodríguez, C, et al.
出版: (2010)

An alkyne hydroacylation route to highly substituted furans.
由: Lenden, P, et al.
出版: (2011)

Rhodium-catalyzed branched-selective alkyne hydroacylation: a ligand-controlled regioselectivity switch.
由: González-Rodríguez, C, et al.
出版: (2011)

Intermolecular hydroacylation: high activity rhodium catalysts containing small-bite-angle diphosphine ligands.
由: Chaplin, AB, et al.
出版: (2012)

Rhodium (I) catalyzed intermolecular hydroacylation.
由: Sapmaz, S, et al.
出版: (2001)

Replacing dichloroethane as a solvent for rhodium-catalysed intermolecular alkyne hydroacylation reactions: the utility of propylene carbonate
由: Lenden, P, et al.
出版: (2011)

Rhodium-catalyzed enantioselective intermolecular hydroacylation reactions
由: Gonzalez-Rodriguez, C, et al.
出版: (2011)

Diversely substituted quinolines via rhodium-catalyzed alkyne hydroacylation
由: Willis, M, et al.
出版: (2016)

Well‐defined and robust rhodium catalysts for the hydroacylation of terminal and internal alkenes
由: Prades, A, et al.
出版: (2015)

Difunctionalization of Alkenes and Alkynes via Intermolecular Radical and Nucleophilic Additions
由: Hongjun Yao, et al.
出版: (2020-12-01)

POP–Type ligands: variable coordination and hemilabile behaviour
由: Adams, G, et al.
出版: (2017)

Synthesis of α,β-unsaturated ketones through nickel-catalysed aldehyde-free hydroacylation of alkynes
由: Joon Ho Rhlee, et al.
出版: (2022-02-01)

An enamine controlling group for rhodium-catalyzed intermolecular hydroacylation
由: Straker, R, et al.
出版: (2018)

Intermolecular hydroacylation of acrylate esters: a new route to 1,4-dicarbonyls
由: Willis, M, et al.
出版: (2001)

Controlling selectivity in the rhodium-catalysed intermolecular hydroacylation reaction
由: Pawley, R
出版: (2012)

Origins of Regioselectivity and Alkene-Directing Effects in Nickel- Catalyzed Reductive Couplings of Alkynes and Aldehydes
由: Jamison, Timothy F., et al.
出版: (2012)

2-Aminobenzaldehydes as versatile substrates for rhodium-catalyzed alkyne hydroacylation: application to dihydroquinolone synthesis.
由: Castaing, M, et al.
出版: (2013)