The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.

Ítems similars

• Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling.
  per: Wykoff, C, et al.
  Publicat: (2000)
• Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene.
  per: Wykoff, C, et al.
  Publicat: (2004)
• The interaction between the von Hippel-Lindau gene product (pVHL) and hypoxia-inducible factor 1 is disrupted by disease-causing pVHL mutants.
  per: Maher, E, et al.
  Publicat: (1999)
• Interaction between the von Hippel-Lindau gene product (pVHL) and hypoxia-inducible factor 1 is disrupted by disease causing pVHL mutants
  per: Clifford, S, et al.
  Publicat: (1999)
• Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
  per: Cockman, M, et al.
  Publicat: (2000)