Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseases.

Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseases.

Preclinical studies have identified and validated tumour necrosis factor alpha (TNFalpha) as a key disease molecule and therapeutic target for immunotherapeutic intervention in many immune-mediated inflammatory diseases. Clinical indications include rheumatoid arthritis, Crohn's disease, ankylo...

Bibliografiset tiedot
Päätekijät:	Taylor, P, Williams, R, Feldmann, M
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2004

Samankaltaisia teoksia

Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha.
Tekijä: Williams, R, et al.
Julkaistu: (2000)

Selective immunosuppression of tumour necrosis factor-alpha in rheumatoid arthritis.
Tekijä: Brennan, F, et al.
Julkaistu: (1995)

What is the mechanism of action of anti-tumour necrosis factor-alpha antibody in rheumatoid arthritis?
Tekijä: Feldmann, M
Julkaistu: (1996)

Beneficial effects of tumour necrosis factor-alpha (TNF-alpha) blockade in rheumatoid arthritis (RA)
Tekijä: Maini, R, et al.
Julkaistu: (1995)

Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumour necrosis factor alpha blockade.
Tekijä: Davis, D, et al.
Julkaistu: (1997)

The effect of tumour necrosis factor-alpha (TNF-alpha) muteins on human neutrophils in vitro.
Tekijä: Tchorzewski, H, et al.
Julkaistu: (1993)

Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.
Tekijä: Culpan, D, et al.
Julkaistu: (2003)

Paradoxical effects of tumour necrosis factor-alpha in adjuvant-induced arthritis.
Tekijä: Williams, R
Julkaistu: (2008)

The role of receptors for tumour necrosis factor-alpha in the induction of human polymorphonuclear neutrophil chemiluminescence.
Tekijä: Zeman, K, et al.
Julkaistu: (1996)

New approaches to therapeutic immunomodulation for immune-mediated inflammatory disorders.
Tekijä: Taylor, P, et al.
Julkaistu: (2004)

Antagonism of tumour necrosis factor alpha in refractory asthma.
Tekijä: Berry, M, et al.
Julkaistu: (2008)

Inhibitory effects of bisbenzylisoquinolines on synthesis of the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha
Tekijä: W. Kim Seow, et al.
Julkaistu: (1993-01-01)

Detection of in vivo production of tumour necrosis factor-alpha by human thyroid epithelial cells.
Tekijä: Zheng, R, et al.
Julkaistu: (1992)

A single-cell therapeutic atlas of anti-tumour necrosis factor therapy in inflammatory bowel disease
Tekijä: Thomas, T, et al.
Julkaistu: (2023)

Tumor necrosis factor-alpha: a promising therapeutic target for asthma?
Tekijä: Heffler, E, et al.
Julkaistu: (2007)

Contrasting effects of interferon gamma and interleukin 4 on responses of human vascular endothelial cells to tumour necrosis factor alpha.
Tekijä: Paleolog, E, et al.
Julkaistu: (1992)

Mechanism of immune complex-mediated damage: induction of interleukin 1 by immune complexes and synergy with interferon-gamma and tumor necrosis factor-alpha.
Tekijä: Chantry, D, et al.
Julkaistu: (1989)

Tumour Necrosis Factor Superfamily Members in the Pathogenesis of Inflammatory Bowel Disease
Tekijä: Tomasz J. Ślebioda, et al.
Julkaistu: (2014-01-01)

Expression of tumour necrosis factor alpha (TNF alpha) and lysozyme in necrotizing enterocolitis (NEC)
Tekijä: Lala, S, et al.
Julkaistu: (2002)

Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis.
Tekijä: Elliott, M, et al.
Julkaistu: (1994)

A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
Tekijä: Thomas, T
Julkaistu: (2023)

The role of tumour necrosis factor alpha stimulated gene-6 on bone
Tekijä: Afrough, S
Julkaistu: (2016)

Current state of tumour necrosis factor {alpha} blockade in Wegener's granulomatosis.
Tekijä: Mukhtyar, C, et al.
Julkaistu: (2005)

Paradoxical Roles of Tumour Necrosis Factor-Alpha in Prostate Cancer Biology
Tekijä: Brian W. C. Tse, et al.
Julkaistu: (2012-01-01)

Increased concentration of tumour necrosis factor alpha in the plasma of glaucoma patients
Tekijä: Trenkić Marija, et al.
Julkaistu: (2024-01-01)

Tumour necrosis factor.
Tekijä: Van Der Merwe, P
Julkaistu: (1988)

Immunomodulatory parasites and toll-like receptor-mediated tumour necrosis factor alpha responsiveness in wild mammals
Tekijä: Ralli Catriona, et al.
Julkaistu: (2009-04-01)

The neutrophil migration induced by tumour necrosis factor alpha in mice is unaffected by glucocorticoids
Tekijä: C. A. Cecilio, et al.
Julkaistu: (1997-01-01)

Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.
Tekijä: Buchan, G, et al.
Julkaistu: (1988)

Anti-tumor necrosis factor alpha therapy of rheumatoid arthritis. Mechanism of action.
Tekijä: Feldmann, M, et al.
Julkaistu: (1997)

Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.
Tekijä: Williams, R, et al.
Julkaistu: (1998)

Endometriosis Classification and The Role of Tumor Necrosis Factor-Alpha Polymorphisms as A Therapeutic Target
Tekijä: Fabio Barra, et al.
Julkaistu: (2020-04-01)

Tumour necrosis factor alpha (TNF) gene haplotypes and primary sclerosing cholangitis
Tekijä: Cullen, SN, et al.
Julkaistu: (2003)

Treatment of intestinal Behcet's syndrome with chimeric tumour necrosis factor alpha antibody.
Tekijä: Travis, S, et al.
Julkaistu: (2001)

Should histoplasmosis be screened for before initiation of tumour necrosis factor alpha inhibitors?
Tekijä: Srujan Edupuganti, et al.
Julkaistu: (2024-04-01)

Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis
Tekijä: Shruthi Hegde, et al.
Julkaistu: (2018-09-01)

Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis
Tekijä: Ananya Madi̇yal, et al.
Julkaistu: (2018-09-01)

Tumour Necrosis Factor-alpha and Nuclear Factor-kappa B Gene Variants in Sepsis
Tekijä: Leyla Acar, et al.
Julkaistu: (2018-02-01)

Tumour necrosis factor synergises with gamma interferon on the induction of mRNA for DR alpha chain on thyrocytes from Graves' disease and non toxic goitre.
Tekijä: Kissonerghis, A, et al.
Julkaistu: (1989)

A comparative study into the mechanisms of action of anti-tumor necrosis factor alpha, anti-CD4, and combined anti-tumor necrosis factor alpha/anti-CD4 treatment in early collagen-induced arthritis.
Tekijä: Marinova-Mutafchieva, L, et al.
Julkaistu: (2000)