Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseases.

Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseases.

Preclinical studies have identified and validated tumour necrosis factor alpha (TNFalpha) as a key disease molecule and therapeutic target for immunotherapeutic intervention in many immune-mediated inflammatory diseases. Clinical indications include rheumatoid arthritis, Crohn's disease, ankylo...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Taylor, P, Williams, R, Feldmann, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2004

समान संसाधन

Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha.
द्वारा: Williams, R, और अन्य
प्रकाशित: (2000)

Selective immunosuppression of tumour necrosis factor-alpha in rheumatoid arthritis.
द्वारा: Brennan, F, और अन्य
प्रकाशित: (1995)

What is the mechanism of action of anti-tumour necrosis factor-alpha antibody in rheumatoid arthritis?
द्वारा: Feldmann, M
प्रकाशित: (1996)

Beneficial effects of tumour necrosis factor-alpha (TNF-alpha) blockade in rheumatoid arthritis (RA)
द्वारा: Maini, R, और अन्य
प्रकाशित: (1995)

Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumour necrosis factor alpha blockade.
द्वारा: Davis, D, और अन्य
प्रकाशित: (1997)

The effect of tumour necrosis factor-alpha (TNF-alpha) muteins on human neutrophils in vitro.
द्वारा: Tchorzewski, H, और अन्य
प्रकाशित: (1993)

Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.
द्वारा: Culpan, D, और अन्य
प्रकाशित: (2003)

Paradoxical effects of tumour necrosis factor-alpha in adjuvant-induced arthritis.
द्वारा: Williams, R
प्रकाशित: (2008)

New approaches to therapeutic immunomodulation for immune-mediated inflammatory disorders.
द्वारा: Taylor, P, और अन्य
प्रकाशित: (2004)

The role of receptors for tumour necrosis factor-alpha in the induction of human polymorphonuclear neutrophil chemiluminescence.
द्वारा: Zeman, K, और अन्य
प्रकाशित: (1996)

Detection of in vivo production of tumour necrosis factor-alpha by human thyroid epithelial cells.
द्वारा: Zheng, R, और अन्य
प्रकाशित: (1992)

Inhibitory effects of bisbenzylisoquinolines on synthesis of the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha
द्वारा: W. Kim Seow, और अन्य
प्रकाशित: (1993-01-01)

Antagonism of tumour necrosis factor alpha in refractory asthma.
द्वारा: Berry, M, और अन्य
प्रकाशित: (2008)

A single-cell therapeutic atlas of anti-tumour necrosis factor therapy in inflammatory bowel disease
द्वारा: Thomas, T, और अन्य
प्रकाशित: (2023)

Tumor necrosis factor-alpha: a promising therapeutic target for asthma?
द्वारा: Heffler, E, और अन्य
प्रकाशित: (2007)

Contrasting effects of interferon gamma and interleukin 4 on responses of human vascular endothelial cells to tumour necrosis factor alpha.
द्वारा: Paleolog, E, और अन्य
प्रकाशित: (1992)

Mechanism of immune complex-mediated damage: induction of interleukin 1 by immune complexes and synergy with interferon-gamma and tumor necrosis factor-alpha.
द्वारा: Chantry, D, और अन्य
प्रकाशित: (1989)

Blocking tumor necrosis factor paved the way for targeted therapeutics in inflammatory diseases
द्वारा: Cong-Qiu Chu, और अन्य
प्रकाशित: (2021-11-01)

Tumour Necrosis Factor Superfamily Members in the Pathogenesis of Inflammatory Bowel Disease
द्वारा: Tomasz J. Ślebioda, और अन्य
प्रकाशित: (2014-01-01)

Expression of tumour necrosis factor alpha (TNF alpha) and lysozyme in necrotizing enterocolitis (NEC)
द्वारा: Lala, S, और अन्य
प्रकाशित: (2002)

Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis.
द्वारा: Elliott, M, और अन्य
प्रकाशित: (1994)

A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
द्वारा: Thomas, T
प्रकाशित: (2023)

The role of tumour necrosis factor alpha stimulated gene-6 on bone
द्वारा: Afrough, S
प्रकाशित: (2016)

Current state of tumour necrosis factor {alpha} blockade in Wegener's granulomatosis.
द्वारा: Mukhtyar, C, और अन्य
प्रकाशित: (2005)

Paradoxical Roles of Tumour Necrosis Factor-Alpha in Prostate Cancer Biology
द्वारा: Brian W. C. Tse, और अन्य
प्रकाशित: (2012-01-01)

Increased concentration of tumour necrosis factor alpha in the plasma of glaucoma patients
द्वारा: Trenkić Marija, और अन्य
प्रकाशित: (2024-01-01)

Tumour necrosis factor.
द्वारा: Van Der Merwe, P
प्रकाशित: (1988)

Immunomodulatory parasites and toll-like receptor-mediated tumour necrosis factor alpha responsiveness in wild mammals
द्वारा: Ralli Catriona, और अन्य
प्रकाशित: (2009-04-01)

Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.
द्वारा: Buchan, G, और अन्य
प्रकाशित: (1988)

Anti-tumor necrosis factor alpha therapy of rheumatoid arthritis. Mechanism of action.
द्वारा: Feldmann, M, और अन्य
प्रकाशित: (1997)

The neutrophil migration induced by tumour necrosis factor alpha in mice is unaffected by glucocorticoids
द्वारा: C. A. Cecilio, और अन्य
प्रकाशित: (1997-01-01)

Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.
द्वारा: Williams, R, और अन्य
प्रकाशित: (1998)

Endometriosis Classification and The Role of Tumor Necrosis Factor-Alpha Polymorphisms as A Therapeutic Target
द्वारा: Fabio Barra, और अन्य
प्रकाशित: (2020-04-01)

Targeting of Tumor Necrosis Factor Alpha Receptors as a Therapeutic Strategy for Neurodegenerative Disorders
द्वारा: Yun Dong, और अन्य
प्रकाशित: (2015-11-01)

Tumour necrosis factor synergises with gamma interferon on the induction of mRNA for DR alpha chain on thyrocytes from Graves' disease and non toxic goitre.
द्वारा: Kissonerghis, A, और अन्य
प्रकाशित: (1989)

Tumour necrosis factor alpha (TNF) gene haplotypes and primary sclerosing cholangitis
द्वारा: Cullen, SN, और अन्य
प्रकाशित: (2003)

Treatment of intestinal Behcet's syndrome with chimeric tumour necrosis factor alpha antibody.
द्वारा: Travis, S, और अन्य
प्रकाशित: (2001)

Should histoplasmosis be screened for before initiation of tumour necrosis factor alpha inhibitors?
द्वारा: Srujan Edupuganti, और अन्य
प्रकाशित: (2024-04-01)

Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis
द्वारा: Shruthi Hegde, और अन्य
प्रकाशित: (2018-09-01)

Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis
द्वारा: Ananya Madi̇yal, और अन्य
प्रकाशित: (2018-09-01)