Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.
The retromer complex mediates retrograde transport of transmembrane cargo from endosomes to the trans-Golgi network (TGN). Mammalian retromer is composed of a sorting nexin (SNX) dimer that binds to phosphatidylinositol 3-phosphate-enriched endosomal membranes and a vacuolar protein sorting (Vps) 26...
Главные авторы: | Rojas, R, van Vlijmen, T, Mardones, G, Prabhu, Y, Rojas, A, Mohammed, S, Heck, A, Raposo, G, van der Sluijs, P, Bonifacino, J |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
Rockefeller University Press
2008
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