Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.
The retromer complex mediates retrograde transport of transmembrane cargo from endosomes to the trans-Golgi network (TGN). Mammalian retromer is composed of a sorting nexin (SNX) dimer that binds to phosphatidylinositol 3-phosphate-enriched endosomal membranes and a vacuolar protein sorting (Vps) 26...
Автори: | , , , , , , , , , |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
Rockefeller University Press
2008
|