Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
With over 450 genes, solute carriers (SLCs) constitute the largest transporter superfamily responsible for the uptake and efflux of nutrients, metabolites, and xenobiotics in human cells. SLCs are associated with a wide variety of human diseases, including cancer, diabetes, and metabolic and neurolo...
Հիմնական հեղինակներ: | Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Huber, KVM |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Frontiers Media
2024
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Նմանատիպ նյութեր
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Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
: Daniela Digles, և այլն
Հրապարակվել է: (2024-07-01) -
The development of a novel high-throughput membrane potential assay and a solid-supported membrane (SSM)-based electrophysiological assay to study the pharmacological inhibition of GLUT9/SLC2A9 isoforms in a drug discovery program
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Հրապարակվել է: (2024-12-01) -
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters
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Հրապարակվել է: (2021-08-01) -
CD4 and the immunoglobulin superfamily.
: Barclay, A, և այլն
Հրապարակվել է: (1993) -
THE IMMUNOGLOBULIN SUPERFAMILY
: Jones, E
Հրապարակվել է: (1993)