Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels

Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels

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Several inwardly-rectifying (Kir) potassium channels (Kin l 1, Kir41 and Kir4 2) are characterised by their sensitivity to inhibition by intracellular H+ within the physiological range The mechanism by which these channels are regulated by intracellular pH has been the subject of intense scrutiny fo...

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Bibliografische gegevens
Hoofdauteurs:	Paynter, J, Shang, L, Bollepalli, M, Baukrowitz, T, Tucker, S
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	LANDES BIOSCIENCE 2010

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