Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes
<p>MHC-E regulates NK cells by displaying MHC class Ia signal peptides (VL9) to NKG2A:CD94 receptors. MHC-E can also present sequence-diverse, lower-affinity, pathogen-derived peptides to T cell receptors (TCRs) on CD8<sup>+</sup> T cells. To understand t...
المؤلفون الرئيسيون: | Walters, LC, Rozbesky, D, Harlos, K, Quastel, M, Sun, H, Springer, S, Rambo, RP, Mohammed, F, Jones, EY, McMichael, AJ, Gillespie, GM |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Cell Press
2022
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مواد مشابهة
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Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes
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منشور في: (2022-06-01) -
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity
حسب: Li, D, وآخرون
منشور في: (2022) -
Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
حسب: Walters, LC, وآخرون
منشور في: (2018) -
Detailed and atypical HLA‐E peptide binding motifs revealed by a novel peptide exchange binding assay
حسب: Walters, LC, وآخرون
منشور في: (2020) -
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding
حسب: Walters, L, وآخرون
منشور في: (2018)