Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery
The addition of fluorescence guidance in laparoscopic procedures has gained significant interest in recent years, particularly through the use of near infrared (NIR) markers. In this work we present a novel laparoscope camera coupler based on an electrically tunable fluidic lens that permits program...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
Optical Society of America
2017
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| _version_ | 1797090130664620032 |
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| author | Volpi, D Tullis, I Barber, P Augustyniak, E Smart, S Vallis, K Vojnovic, B |
| author_facet | Volpi, D Tullis, I Barber, P Augustyniak, E Smart, S Vallis, K Vojnovic, B |
| author_sort | Volpi, D |
| collection | OXFORD |
| description | The addition of fluorescence guidance in laparoscopic procedures has gained significant interest in recent years, particularly through the use of near infrared (NIR) markers. In this work we present a novel laparoscope camera coupler based on an electrically tunable fluidic lens that permits programmable focus control and has desirable achromatic performance from the visible to the NIR. Its use extends the lower working distance limit and improves detection sensitivity, important for work with molecularly targeted fluorescence markers. We demonstrate its superior optical performance in laparoscopic fluorescence-guided surgery. In vivo results using a tumor specific molecular probe and a nonspecific NIR dye are presented. |
| first_indexed | 2024-03-07T03:14:06Z |
| format | Journal article |
| id | oxford-uuid:b532eff8-352c-4bbb-81e2-92d421570faf |
| institution | University of Oxford |
| last_indexed | 2024-03-07T03:14:06Z |
| publishDate | 2017 |
| publisher | Optical Society of America |
| record_format | dspace |
| spelling | oxford-uuid:b532eff8-352c-4bbb-81e2-92d421570faf2022-03-27T04:31:40ZElectrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgeryJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b532eff8-352c-4bbb-81e2-92d421570fafSymplectic Elements at OxfordOptical Society of America2017Volpi, DTullis, IBarber, PAugustyniak, ESmart, SVallis, KVojnovic, BThe addition of fluorescence guidance in laparoscopic procedures has gained significant interest in recent years, particularly through the use of near infrared (NIR) markers. In this work we present a novel laparoscope camera coupler based on an electrically tunable fluidic lens that permits programmable focus control and has desirable achromatic performance from the visible to the NIR. Its use extends the lower working distance limit and improves detection sensitivity, important for work with molecularly targeted fluorescence markers. We demonstrate its superior optical performance in laparoscopic fluorescence-guided surgery. In vivo results using a tumor specific molecular probe and a nonspecific NIR dye are presented. |
| spellingShingle | Volpi, D Tullis, I Barber, P Augustyniak, E Smart, S Vallis, K Vojnovic, B Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery |
| title | Electrically tunable fluidic lens imaging
system for laparoscopic fluorescence-guided
surgery |
| title_full | Electrically tunable fluidic lens imaging
system for laparoscopic fluorescence-guided
surgery |
| title_fullStr | Electrically tunable fluidic lens imaging
system for laparoscopic fluorescence-guided
surgery |
| title_full_unstemmed | Electrically tunable fluidic lens imaging
system for laparoscopic fluorescence-guided
surgery |
| title_short | Electrically tunable fluidic lens imaging
system for laparoscopic fluorescence-guided
surgery |
| title_sort | electrically tunable fluidic lens imaging system for laparoscopic fluorescence guided surgery |
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