The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair

Double-strand breaks (DSBs) are critical DNA lesions that robustly activate the elaborate DNA damage response (DDR) network. We identified a critical player in DDR fine-tuning: the E3/E4 ubiquitin ligase UBE4A. UBE4A's recruitment to sites of DNA damage is dependent on primary E3 ligases in the...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Baranes-Bachar, K, Levy-Barda, A, Oehler, J, Reid, D, Soria-Bretones, I, Voss, T, Chung, D, Park, Y, Liu, C, Yoon, J, Li, W, Dellaire, G, Misteli, T, Huertas, P, Rothenberg, E, Ramadan, K, Ziv, Y, Shiloh, Y
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Cell Press 2018

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair

Những quyển sách tương tự