Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)

<p><strong>Purpose</strong> Noncontrast 4D‐MR‐angiography (MRA) using arterial spin labeling (ASL) is beneficial because high spatial and temporal resolution can be achieved. However, ASL requires acquisition of labeled and control images for each phase. The purpose of this study i...

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主要な著者: Suzuki, Y, Fujima, N, Ogino, T, Meakin, J, Suwa, A, Sugimori, H, Van Cauteren, M, Van Osch, M
フォーマット: Journal article
言語:English
出版事項: Wiley 2017
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author Suzuki, Y
Fujima, N
Ogino, T
Meakin, J
Suwa, A
Sugimori, H
Van Cauteren, M
Van Osch, M
author_facet Suzuki, Y
Fujima, N
Ogino, T
Meakin, J
Suwa, A
Sugimori, H
Van Cauteren, M
Van Osch, M
author_sort Suzuki, Y
collection OXFORD
description <p><strong>Purpose</strong> Noncontrast 4D‐MR‐angiography (MRA) using arterial spin labeling (ASL) is beneficial because high spatial and temporal resolution can be achieved. However, ASL requires acquisition of labeled and control images for each phase. The purpose of this study is to present a new accelerated 4D‐MRA approach that requires only a single control acquisition, achieving similar image quality in approximately half the scan time.</p> <p><strong>Methods</strong> In a multi‐phase Look‐Locker sequence, the first phase was used as the control image and the labeling pulse was applied before the second phase. By acquiring the control and labeled images within a single Look‐Locker cycle, 4D‐MRA was generated in nearly half the scan time of conventional ASL. However, this approach potentially could be more sensitive to off‐resonance and magnetization transfer (MT) effects. To counter this, careful optimizations of the labeling pulse were performed by Bloch simulations. In in‐vivo studies arterial visualization was compared between the new and conventional ASL approaches.</p> <p><strong>Results</strong> Optimization of the labeling pulse successfully minimized off‐resonance effects. Qualitative assessment showed that residual MT effects did not degrade visualization of the peripheral arteries.</p> <p><strong>Conclusion</strong> This study demonstrated that the proposed approach achieved similar image quality as conventional ASL‐MRA approaches in just over half the scan time.</p>
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spelling oxford-uuid:b54d4064-be15-4af7-9d54-4081481ba6192022-03-27T04:32:31ZAcceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b54d4064-be15-4af7-9d54-4081481ba619EnglishSymplectic Elements at OxfordWiley2017Suzuki, YFujima, NOgino, TMeakin, JSuwa, ASugimori, HVan Cauteren, MVan Osch, M<p><strong>Purpose</strong> Noncontrast 4D‐MR‐angiography (MRA) using arterial spin labeling (ASL) is beneficial because high spatial and temporal resolution can be achieved. However, ASL requires acquisition of labeled and control images for each phase. The purpose of this study is to present a new accelerated 4D‐MRA approach that requires only a single control acquisition, achieving similar image quality in approximately half the scan time.</p> <p><strong>Methods</strong> In a multi‐phase Look‐Locker sequence, the first phase was used as the control image and the labeling pulse was applied before the second phase. By acquiring the control and labeled images within a single Look‐Locker cycle, 4D‐MRA was generated in nearly half the scan time of conventional ASL. However, this approach potentially could be more sensitive to off‐resonance and magnetization transfer (MT) effects. To counter this, careful optimizations of the labeling pulse were performed by Bloch simulations. In in‐vivo studies arterial visualization was compared between the new and conventional ASL approaches.</p> <p><strong>Results</strong> Optimization of the labeling pulse successfully minimized off‐resonance effects. Qualitative assessment showed that residual MT effects did not degrade visualization of the peripheral arteries.</p> <p><strong>Conclusion</strong> This study demonstrated that the proposed approach achieved similar image quality as conventional ASL‐MRA approaches in just over half the scan time.</p>
spellingShingle Suzuki, Y
Fujima, N
Ogino, T
Meakin, J
Suwa, A
Sugimori, H
Van Cauteren, M
Van Osch, M
Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)
title Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)
title_full Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)
title_fullStr Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)
title_full_unstemmed Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)
title_short Acceleration of ASL‐based time‐resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS)
title_sort acceleration of asl based time resolved mr angiography by acquisition of control and labeled images in the same shot actress
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