PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks

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Poly adenosine diphosphate (ADP)-ribosylation (PARylation) by poly ADP-ribose (PAR) polymerases (PARPs) is an early response to DNA double-strand breaks (DSBs). In this paper, we exploit Dictyostelium discoideum to uncover a novel role for PARylation in regulating nonhomologous end joining (NHEJ). P...

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Bibliographic Details
Main Authors:	Couto, C, Wang, H, Green, J, Kiely, R, Siddaway, R, Borer, C, Pears, C, Lakin, N
Format:	Journal article
Language:	English
Published:	2011

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