The impact of trisomy 21 on foetal haematopoiesis.

The high frequency of a unique neonatal preleukaemic syndrome, transient abnormal myelopoiesis (TAM), and subsequent acute myeloid leukaemia in early childhood in patients with trisomy 21 (Down syndrome) points to a specific role for trisomy 21 in transforming foetal haematopoietic cells. N-terminal...

Full description

Bibliographic Details
Main Authors: Roberts, I, O'Connor, D, Roy, A, Cowan, G, Vyas, P
Format: Journal article
Language:English
Published: 2013