The impact of trisomy 21 on foetal haematopoiesis.

The high frequency of a unique neonatal preleukaemic syndrome, transient abnormal myelopoiesis (TAM), and subsequent acute myeloid leukaemia in early childhood in patients with trisomy 21 (Down syndrome) points to a specific role for trisomy 21 in transforming foetal haematopoietic cells. N-terminal...

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Main Authors: Roberts, I, O'Connor, D, Roy, A, Cowan, G, Vyas, P
格式: Journal article
语言:English
出版: 2013