TNFR2: The new Treg switch?
Three recent publications identified the TNF/TNR2 pathway as a new target to reduce graft-versus-host-disease through regulatory T cells activation or to potentially switch on a strong anti-leukemic effect through regulatory T cells blockade in allogeneic hematopoietic stem cell transplantation. Thi...
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Taylor and Francis
2017
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| _version_ | 1826292456006615040 |
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| author | Cohen, JL Wood, KJ |
| author_facet | Cohen, JL Wood, KJ |
| author_sort | Cohen, JL |
| collection | OXFORD |
| description | Three recent publications identified the TNF/TNR2 pathway as a new target to reduce graft-versus-host-disease through regulatory T cells activation or to potentially switch on a strong anti-leukemic effect through regulatory T cells blockade in allogeneic hematopoietic stem cell transplantation. This identified the TNF/TNR2 pathway as a swith and as a new target for immune checkpoint therapy to modulate the immune regulation in this clinical setting. |
| first_indexed | 2024-03-07T03:14:58Z |
| format | Journal article |
| id | oxford-uuid:b57eac31-a8d1-4a9f-830e-41d42fe9ce57 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:14:58Z |
| publishDate | 2017 |
| publisher | Taylor and Francis |
| record_format | dspace |
| spelling | oxford-uuid:b57eac31-a8d1-4a9f-830e-41d42fe9ce572022-03-27T04:33:44ZTNFR2: The new Treg switch?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b57eac31-a8d1-4a9f-830e-41d42fe9ce57EnglishSymplectic Elements at OxfordTaylor and Francis2017Cohen, JLWood, KJThree recent publications identified the TNF/TNR2 pathway as a new target to reduce graft-versus-host-disease through regulatory T cells activation or to potentially switch on a strong anti-leukemic effect through regulatory T cells blockade in allogeneic hematopoietic stem cell transplantation. This identified the TNF/TNR2 pathway as a swith and as a new target for immune checkpoint therapy to modulate the immune regulation in this clinical setting. |
| spellingShingle | Cohen, JL Wood, KJ TNFR2: The new Treg switch? |
| title | TNFR2: The new Treg switch? |
| title_full | TNFR2: The new Treg switch? |
| title_fullStr | TNFR2: The new Treg switch? |
| title_full_unstemmed | TNFR2: The new Treg switch? |
| title_short | TNFR2: The new Treg switch? |
| title_sort | tnfr2 the new treg switch |
| work_keys_str_mv | AT cohenjl tnfr2thenewtregswitch AT woodkj tnfr2thenewtregswitch |