A potential role for psilocybin in the treatment of obsessive-compulsive disorder
The recent revivification of interest in the therapeutic use of psychedelics has had a particular focus on mood disorders and addiction, although there is reason to think these drugs may be effective more widely. After outlining pertinent aspects of psilocybin and obsessive-compulsive disorder (OCD)...
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| Format: | Journal article |
| Language: | English |
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Akadémiai Kiadó
2020
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| _version_ | 1797090202428112896 |
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| author | Jacobs, E |
| author_facet | Jacobs, E |
| author_sort | Jacobs, E |
| collection | OXFORD |
| description | The recent revivification of interest in the therapeutic use of psychedelics has had a particular focus on mood disorders and addiction, although there is reason to think these drugs may be effective more widely. After outlining pertinent aspects of psilocybin and obsessive-compulsive disorder (OCD), the current review summarizes the evidence indicating that there may be a role for psilocybin in the treatment of OCD, as well as highlighting a range of potential therapeutic mechanisms that reflect the action of psilocybin on brain function. Although the current evidence is limited, that multiple signals point in directions consistent with treatment potential, alongside the psychological and physiological safety of clinically administered psilocybin, support the expansion of research, both in animal models and in further randomized controlled trials, to properly investigate this potential. |
| first_indexed | 2024-03-07T03:15:07Z |
| format | Journal article |
| id | oxford-uuid:b5883ecc-c618-4dfa-879a-67302314e2b6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:15:07Z |
| publishDate | 2020 |
| publisher | Akadémiai Kiadó |
| record_format | dspace |
| spelling | oxford-uuid:b5883ecc-c618-4dfa-879a-67302314e2b62022-03-27T04:34:12ZA potential role for psilocybin in the treatment of obsessive-compulsive disorderJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b5883ecc-c618-4dfa-879a-67302314e2b6EnglishSymplectic ElementsAkadémiai Kiadó2020Jacobs, EThe recent revivification of interest in the therapeutic use of psychedelics has had a particular focus on mood disorders and addiction, although there is reason to think these drugs may be effective more widely. After outlining pertinent aspects of psilocybin and obsessive-compulsive disorder (OCD), the current review summarizes the evidence indicating that there may be a role for psilocybin in the treatment of OCD, as well as highlighting a range of potential therapeutic mechanisms that reflect the action of psilocybin on brain function. Although the current evidence is limited, that multiple signals point in directions consistent with treatment potential, alongside the psychological and physiological safety of clinically administered psilocybin, support the expansion of research, both in animal models and in further randomized controlled trials, to properly investigate this potential. |
| spellingShingle | Jacobs, E A potential role for psilocybin in the treatment of obsessive-compulsive disorder |
| title | A potential role for psilocybin in the treatment of obsessive-compulsive disorder |
| title_full | A potential role for psilocybin in the treatment of obsessive-compulsive disorder |
| title_fullStr | A potential role for psilocybin in the treatment of obsessive-compulsive disorder |
| title_full_unstemmed | A potential role for psilocybin in the treatment of obsessive-compulsive disorder |
| title_short | A potential role for psilocybin in the treatment of obsessive-compulsive disorder |
| title_sort | potential role for psilocybin in the treatment of obsessive compulsive disorder |
| work_keys_str_mv | AT jacobse apotentialroleforpsilocybininthetreatmentofobsessivecompulsivedisorder AT jacobse potentialroleforpsilocybininthetreatmentofobsessivecompulsivedisorder |