Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products.
The selective knockdown of genes using RNA interference, and the analysis of the resultant phenotype using calcium imaging, is proving to be a powerful combination for discovering new genes involved in calcium signalling. This technical note describes the application of this approach to the Drosophi...
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| Format: | Journal article |
| Language: | English |
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2006
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| _version_ | 1797090216095252480 |
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| author | Buckingham, S |
| author_facet | Buckingham, S |
| author_sort | Buckingham, S |
| collection | OXFORD |
| description | The selective knockdown of genes using RNA interference, and the analysis of the resultant phenotype using calcium imaging, is proving to be a powerful combination for discovering new genes involved in calcium signalling. This technical note describes the application of this approach to the Drosophila S2 cell line and its derivatives. |
| first_indexed | 2024-03-07T03:15:19Z |
| format | Journal article |
| id | oxford-uuid:b595d0c7-83eb-42ea-badb-91ec1c4e29bb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:15:19Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:b595d0c7-83eb-42ea-badb-91ec1c4e29bb2022-03-27T04:34:33ZFunctional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b595d0c7-83eb-42ea-badb-91ec1c4e29bbEnglishSymplectic Elements at Oxford2006Buckingham, SThe selective knockdown of genes using RNA interference, and the analysis of the resultant phenotype using calcium imaging, is proving to be a powerful combination for discovering new genes involved in calcium signalling. This technical note describes the application of this approach to the Drosophila S2 cell line and its derivatives. |
| spellingShingle | Buckingham, S Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products. |
| title | Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products. |
| title_full | Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products. |
| title_fullStr | Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products. |
| title_full_unstemmed | Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products. |
| title_short | Functional genomics: applying calcium imaging and RNA interference to Drosophila cell lines to identify new roles for gene products. |
| title_sort | functional genomics applying calcium imaging and rna interference to drosophila cell lines to identify new roles for gene products |
| work_keys_str_mv | AT buckinghams functionalgenomicsapplyingcalciumimagingandrnainterferencetodrosophilacelllinestoidentifynewrolesforgeneproducts |