Biological relevance of DNA polymerase β and translesion synthesis polymerases to cancer and its treatment.

Biological relevance of DNA polymerase β and translesion synthesis polymerases to cancer and its treatment.

The cellular genome is constantly subject to DNA damage caused by endogenous factors or exogenously by damaging agents such as ionizing radiation or various anticancer agents. The base excision repair (BER) enzyme, DNA polymerase β, and the polymerases involved in translesion synthesis (TLS) have be...

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Chi tiết về thư mục
Những tác giả chính:	Nicolay, N, Helleday, T, Sharma, R
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2012

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