The gata1/pu.1 lineage fate paradigm varies between blood populations and is modulated by tif1γ.
Lineage fate decisions underpin much of development as well as tissue homeostasis in the adult. A mechanistic paradigm for such decisions is the erythroid versus myeloid fate decision controlled by cross-antagonism between gata1 and pu.1 transcription factors. In this study, we have systematically t...
Hlavní autoři: | Monteiro, R, Pouget, C, Patient, R |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2011
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