Increased transplant arteriosclerosis in the absence of CCR7 is associated with reduced expression of Foxp3.

BACKGROUND: The chemokine receptor CCR7 plays a pivotal role in the homing of naïve T cells and regulatory T cells to secondary lymphoid organs and the migration of dendritic cells into afferent lymphatic vessels. Antigen presentation, T cell recruitment, and expansion of regulatory cells are cruci...

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Main Authors: Ensminger, S, Helm, SN, Ohl, L, Spriewald, B, Abele, S, Wollin, M, Wood, K, Weyand, M, Förster, R
格式: Journal article
语言:English
出版: 2008